What is the first line treatment for Schistosomiasis?

The first-line treatment for schistosomiasis is praziquantel. This medication is specifically effective against the adult worms of the Schistosoma genus, which are responsible for the disease. Praziquantel works by causing severe spasms and paralysis of the schistosomes, leading to their detachment from blood vessels and eventual death. It is well-tolerated and has a proven track record of efficacy in treating various forms of schistosomiasis, making it the gold standard for this infection.

Other treatments like albendazole and ivermectin target different parasites and are not effective against schistosomiasis. Albendazole is primarily used for infections caused by certain helminths such as hookworm and tapeworms, while ivermectin is effective for nematodes and ectoparasites like lice and scabies. Diethylcarbamazine is used for filariasis and certain other parasitic infections but does not have activity against schistosomiasis. Thus, praziquantel is the most appropriate choice for treating this specific condition.